Hamadan University of Medical Sciences Avicenna Journal of Medical Biochemistry 2345-4113 3 1 2015 03 01 The Impact of G1575A Matrix Metalloprotease-2 Gene Polymorphism on Male Fertility 6 27826 10.17795/ajmb-27826 EN Aboozar Mohagheghi Iraj Khodadadi Manoochehr Karami Iraj Amiri Heidar Tavilani Journal Article 10.17795/ajmb-27826 2015 02 05 2015 02 22 Background: Matrix metalloproteinases contain more than 20 enzymes that require zinc for their activities. Gelatinases are one of the subtypes of matrixmetalloproteinases, which degrade gelatin and collagen type 4, and are present in male reproductive tissues such as in prostate. G1575A Matrix Metalloproteinase-2 (MMP-2) gene polymorphism affects MMP-2 activity.