Hamadan University of Medical Sciences Avicenna Journal of Medical Biochemistry 2345-4113 4 1 2016 06 01 Effect of Aerobic Training Program on Serum C-reactive Protein Levels 8 33294 10.17795/ajmb-33294 EN Mojtaba Eizadi Shahram Sohaily Davood Khorshidi Hamidreza Samarikhalaj Journal Article 10.17795/ajmb-33294 2015 09 20 2015 10 31 Background: Smoking is an established risk factor for cardiovascular diseases and metabolic syndrome. Objectives: Here we aimed to assess the effect of 3-month aerobic training on C-reactive protein (CRP) level and total antioxidant capacity (TAC) in male smokers. Patients and Methods: A total of 34 male cigarette smokers aged 35 – 45 years participated in this study by accessible sampling and were divided randomly into experimental and control groups. Pre- and post-training CRP and TAC data were collected in both groups and compared by Student’s t-test. Results: Aerobic training resulted in a significantly increased TAC (P < 0.001), but CRP remained unchanged (P = 0.96). Conclusions: Despite a lack of CRP change, long-term aerobic training is associated with anti-oxidative effects.