Reham Z. Hamza
1,2 
, Fawzeh A. Al-Salmi
1, Nahla S. El-Shenawy
3* 1 Biology Department, Faculty of Science, Taif University, Taif, Saudi Arabia.
2 Zoology Department, Faculty of Science, Zagazig University, Zagazig, Egypt.
3 Zoology Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt.
*Corresponding Author: *Corresponding author: Nahla S El-Shenawy, Zoology Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt. Tel: 002/01008660620; Email: elshenawy_nahla@ hotmail.com. , Email:
nahla.el-shennawy@scuegypt. edu.eg
Abstract
This brief review provided evidence for the role of green tea extract (GTE)/zinc oxide nanoparticles (ZnO NPs) in a variety of biomedical applications against the toxic effect of monosodium glutamate (MSG). MSG is used to enhance the taste, however it causes oxidative stress in the long-term. Many effects of MSG consumption on the brain, obesity, sex organs, and metabolism have been verified. This review covered the effect of GTE/ZnO NPs on many different organs including the liver, kidney, heart, spleen, testis, brain, and pancreas after being exposed to MSG. The review indicated that the toxicity induced by MSG could be restored by GTE/ZnO NPs in different organs. Accordingly, the green nanoparticles could be attended as a futuristic approach to be used against any toxic substance.